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Prohormones are precursors of hormones which are formed in the body. It has for many years been able to buy prohormones as dietary supplements in the United States and other countries, and they had at some point also gained some popularity. It is not allowed to sell prohormones and best sarms online in USA and they are also on the doping list.
What are anabolic steroids?
The concept of steroids covers molecules that are based on a sterolmolekyle starting from cholesterol. Androgen is a term used for all drugs, natural and synthetic, that binds to the androgen receptors, and thus has a stimulating effect on the masculine sex characteristics.
Androgenic means “on the masculine sex characteristics” and anabolic means tissue engineering. Androgenic anabolic steroids is all cholesterol-like compounds which are tissue engineering and which can provide certain masculinizing effects. It covers both the male sex hormone testosterone, but also of known doping substances such as Dianabol, oxymethelon so on. The vast majority of anabolic steroids on the market is synthetic, that is to say that they have been “built” in a laboratory. Their structure is usually derived from the male sex hormone testosterone, but often modified in various ways, either to make the drug more potent, making it ingestible by mouth or to increase its life in the body.
It has for many years attempted to separate the tissue-building effect of the androgen, showing the androgenic side (eg, aggressiveness, accelerated hair loss and oily skin) as undesirable compared to the anabolic. The kind has only had limited success. The most potent anabolic steroids are roughly speaking also the strongest androgenic.
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The side effects of anabolic steroids
Anabolic steroids have a very broad spectrum and thus also a whole range of physical side effects. In general, one can say that there are some side effects are acute / transient and some that are wholly or partially chronic. The acute are those which are seen only as long as anabolic steroids in the body and chronic are the effects that remain in the body even after the steroids are out.
For both the acute and chronic effects it applies that the greater the dose, the greater side effects. For the chronic side effects applies that effect accumulates over time. This means that some side effects look forward to cures, and some others only after 10 cures and of course there is a tremendous big difference between individuals with regard to this.
The acute side effects most often seen are:
- oily skin / acne
- set up own production of testosterone
- decreased cholesterol
- fatigue or slightly increased irritability (depending on which medicines they are on)
Generally it takes several cures before the chronic side effects begin to come, but when they do, are the most frequent chronic side effects:
- the accelerated baldness
- enlargement of the prostate
- stiffer heart muscle
The side effects of prolonged drug use, poorly lit that it’s hard to put proper studies up because drug use is so taboo. On the one hand, there are many controlled studies with anabolic steroids, having document no or few side effects at 3-4 months of treatment with steroids, even in fairly high doses. On the other hand, there are hundreds of case studies documenting organ failure, depression or other serious adverse events following the use of anabolic steroids.
This discrepancy is probably explained by the accumulated consumption of anabolic steroids should be above a certain threshold value until the effects really begin to look forward. A single study followed the mortality of steroid users over 12 years and found a clear increase in mortality, primarily due to cardiovascular disease and suicide, according to the background population so it can easily be said that there all are some health problems associated with using anabolic steroids, but the problem is still not well documented.
What is the situation so with prohormones?
All steroid hormones in our body formed into so-called synthesis chains in which the first converted from one type of connection to the second and the next until they reach the “target”. In this way, for example, 6 individual steps from cholesterol to testosterone. The idea of prohormones is supplying the body a molecule that is part of a chain found at the step just before the formation of the desired active substance.
Then by adding more of it turns into testosterone or other anabolic steroid in the next step, it is hoped to “push” the reaction is little, so there will be formed more of the active substance and thus obtain a performance enhancing or tissue engineering effect. Unfortunately the prohormones generally not very good, but has approximately the same risk of side effects as “real” anabolic steroids. In addition, the prohormones also the same risks to test positive in doping tests as you do with real anabolic steroids.